Member Profile

Ovide F. Pomerleau, PhD
Professor of Psychology, Psychiatry Department

Nicotine Research Laboratory
Behavioral Medicine Program
UM Department of Psychiatry
Rachel Upjohn Building, Room 2137
4250 Plymouth Road
Ann Arbor, MI 48109-5765

Phone (734) 232-0384
Fax (734) 615-8739
ofpom@umich.edu

Scientific Research Discipline(s)

Department of Psychiatry; School of Medicine; Psychology

Tobacco & Nicotine Related Interests & Expertise

Biobehavioral research, underlying mechanisms and genetics of smoking and nicotine dependence, pharmacology: drug action and mechanisms

Recent Publications on Tobacco/Nicotine

Sherva R, Wilhelmsen K, Pomerleau CS, Chasse SA, Rice JP, Snedecor SM, Bierut LJ, Neuman RJ, Pomerleau OF - 2008
"Association of a SNP in neuronal acetylcholine receptor subunit alpha 5 (CHRNA5) with smoking status and with 'pleasurable buzz' during early experimentation with smoking"
Addiction (accepted for publication)

Strecher VJ, McClure J, Alexander G, Chakraborty B, Nair V, Konkel J, Greene S, Collins L, Carlier C, Wiese C, Little R, Pomerleau C, and Pomerleau O - 2008
"Web-Based Smoking Cessation Program: Results of a Randomized Trial"
American Journal of Preventive Medicine May 34(5)

Bierut LJ, Madden PA, Breslau N, Johnson EO, Hatsukami D, Pomerleau OF, Swan GE, Rutter J, Bertelsen S, Fox L, Fugman D, Goate AM, Hinrichs AL, Konvicka K, Martin NG, Montgomery GW, Saccone NL, Saccone SF, Wang JC, et al. - 2008
"Novel genes identified in a high density genome wide association study for nicotine dependence"
Human Molecular Genetics (in press) [Epub ahead of print 12/7/2006]

Pomerleau OF, Pomerleau CS, Chu J, Kardia SLR - 2007
"Genome-wide linkage analysis for smoking-related genomic regions with replication in two ethnically diverse populations"
Nicotine & Tobacco Research 9:955-958

Pomerleau OF, Burmeister M, Madden P, Long J, Swan GE, Kardia SLR - 2007
"Genetic research on complex behaviors: An examination of attempts to identify genes for smoking"
Nicotine & Tobacco Research 9:883-901

Saccone SF, Hinrichs AL, Saccone NL, Chase GA, Konvicka K, Madden PA, Breslau N, Johnson EO, Hatsukami D, Pomerleau OF, Swan GE, Goate AM, Rutter J, Bertelsen S, Fox L, Fugman D, Martin NG, Montgomery GW, Wang JC, et al. - 2007
"Cholinergic nicotinic receptor genes implicated in a nicotine dependence association study Targeting 348 Candidate Genes with 3,713 SNPs"
Human Molecular Genetics 16:24-35 [Epub ahead of print 11/29/06]

Snedecor SM, Pomerleau CS, Mehringer AM, Ninowski R, Pomerleau OF - 2006
"Differences in smoking-related variables based on phenylthiocarbamide 'taster' status"
Addictive Behaviors 39:2301-2312

Pomerleau OF, Pomerleau CS, Mehringer AM, Snedecor SM, Ninowski R, Sen A - 2005
"Nicotine dependence, depression, and gender: Characterizing phenotypes based on withdrawal discomfort, response to smoking, and ability to abstain"
Nicotine & Tobacco Research 7:91-102

Pomerleau OF, Pomerleau CS, Mehringer AM, Snedecor SM, Cameron OG - 2005
"Validation of retrospective reports of early experiences with smoking"
Addictive Behaviors 30:607-611

Pomerleau CS, Snedecor S, Ninowski R, Gaulrapp S, Pomerleau OF, Kardia SLR - 2005
"Differences in accuracy of offspring assessment based on parental smoking status"
Addictive Behaviors 3:437-441

Karam-Hage M, Pomerleau CS, Pomerleau OF, Brower KJ - 2005
"Unaided smoking cessation at six-month follow-up in smokers in treatment for alcohol dependence"
Addictive Behaviors 30:1247-1253

Pomerleau OF, Hughes JR - 2004
"With a little help from its friends: A brief history of the Society for Research on Nicotine and Tobacco"
Nicotine & Tobacco Research 6:391-395

Pomerleau CS, Pomerleau OF, Snedecor SM, Mehringer AM - 2004
"Defining a never-smoker: Results from the Nonsmokers Survey"
Addictive Behaviors 29:1149-1154

Pomerleau CS, Marks JL, Pomerleau OF, Snedecor SM - 2004
"Relationship between early experiences with tobacco and early experiences with alcohol"
Addictive Behaviors 29:1245-1251

Pomerleau CS, Pomerleau OF, Snedecor SM, Gaulrapp S, Kardia SLR - 2004
"Heterogeneity in phenotypes based on smoking status in the Great Lakes Smoker Sibling Registry"
Addictive Behaviors 29:1851-1855

Pomerleau OF, Pomerleau CS, Snedecor SM, Gaulrapp S, Brouwer RN, Cameron OG - 2004
"Depression, smoking abstinence, and HPA function in women smokers"
Human Psychopharmacology: Clinical & Experimental 19:467-476

Pomerleau OF, Pomerleau CS, Marks JL, Snedecor SM, Mehringer AM, Namenek Brouwer RJ, Saules KK - 2003
"Prolonged nicotine patch use in quitters with past abstinence-induced depression"
Journal of Substance Abuse Treatment 24:13-18

Pomerleau OF, Fagerstrom K-O, Marks JL, Tate JC, Pomerleau CS - 2003
"Development and validation of a scale for assessing positive- and negative-reinforcement smoking: The Michigan Nicotine Reinforcement Questionnaire"
Nicotine & Tobacco Research 5:711-718

Benowitz NL, Pomerleau OF, Pomerleau CS, Jacob P III - 2003
"Nicotine metabolite ratio as a predictor of cigarette consumption"
Nicotine & Tobacco Research 5:621-624

Pomerleau CS, Downey KK, Snedecor SM, Mehringer AM, Marks JL, Pomerleau OF - 2003
"Smoking patterns and abstinence effects in smokers with no ADHD, childhood ADHD, and adult ADHD symptomatology"
Addictive Behaviors 28:1149-1157

Marks JL, Swan G, Pomerleau CS, Pomerleau OF - 2003
"Agreement between proband and parental self-report of smoking behavior"
Nicotine & Tobacco Research 5:527-533

Trask PC, Schwartz SM, Deaner SL, Paterson AG, Johnson T, Rubenfire M, Pomerleau OF - 2002
"Behavioral Medicine: The challenge of integrating psychological and behavioral approaches into Primary Care"
Effective Clinical Practice 5:75-83

Pomerleau CS, Namenek Brouwer RJ, Pomerleau OF - 2001
"Emergence of depression during early abstinence in depressed and non-depressed women smokers"
Journal of Addictive Diseases 20:73-80

Pomerleau CS, Zucker AN, Namenek Brouwer RJ, Pomerleau OF, Stewart AJ - 2001
"Race differences in weight concerns among women smokers: Results from two independent samples"
Addictive Behaviors 26:651-653

Pomerleau OF, Pomerleau CS, Marks JL - 2000
"Abstinence effects and reactivity to nicotine during eleven days of smoking deprivation"
Nicotine & Tobacco Research 2:149-157

Pomerleau CS, Mehringer AM, Marks JL, Downey KK, Pomerleau OF - 2000
"Effects of menstrual phase and smoking abstinence in smokers with and without a history of Major Depressive Disorder"
Addictive Behaviors 25:483-497

Pomerleau CS, Pomerleau OF, Namenek RJ, Mehringer AM - 2000
"Short-term weight gain in abstaining women smokers"
Journal of Substance Abuse Treatment 18:339-342

Pomerleau CS, Marks JL, Pomerleau OF - 2000
"Who gets what symptom? Effects of psychiatric cofactors and nicotine dependence on patterns of nicotine withdrawal symptomatology"
Nicotine & Tobacco Research 2:275-280

Recent Tobacco/Nicotine-related Grants/Contracts

2003-2008
Michigan Center for Health Communications Research (includes: "Studying the active components of smoking interventions" and "Theory and Measurement Core")
$ 9,998,585 National Cancer Institute (Co-Investigator with Victor Strecher, Principal Investigator)

2003-2008
Genes for smoking in related and unrelated individuals
$ 631,137 National Institute on Drug Abuse (PI)

2002-2007
Effects of family smoking history in never-smokers
$ 2,469,889 National Institute on Drug Abuse (PI)

2003-2007
Effectiveness of tailoring depth in Web-based smoking interventions
$ 2,870,378 National Cancer Institute (Co-Investigator with Victor Strecher, Principal Investigator)

2000-2005
Differentiation of Phenotypes for Smoking
$ 1,099,285 National Institute on Drug Abuse (PI)

2000-2004
Differentiation of phenotypes for smoking - Administrative Supplement
$ 1,331,851 National Institute on Drug Abuse (PI)

1999-2004
Interdisciplinary Training Program: From Bench to Bedside
$ 1,275,000 National Institute of Drug Abuse

1998-2004
Pharmacokinetics of Nicotine in Twins
$ 17,000 National Institute on Drug Abuse (co-PI with Gary Swan, Principal Investigator)

1999-2002
Genetics of Smoking and Nicotine Dependence in Families
$ 263,160 National Cancer Institute (PI)

1997-2002
Nicotine Dependence and Withdrawal in Adult ADHD (component of Program Project, "Neuroscience of Nicotine Dependence and Cofactors")
$ 283,200 National Cancer Institute (co-PI with Cynthia S. Pomerleau, Principal Investigator)

1996-2002
Depression, HPA Function, & Smoking Abstinence in Women
$ 1,305,750 National Cancer Institute (PI)

2000-2001
Phenotypic and genotypic differences in sibling pairs concordant and discordant for smoking
$ 15,000 Munn Research Grant, University of Michigan Comprehensive Cancer Center

1997-2001
Neuroscience of Nicotine Dependence and Co-factors
$ 2,872,220 NIH

1995-2001
Bingeing and Weight Gain upon Smoking Cessation in Women
$ 523,506 National Heart, Lung, and Blood Institute (co-PI with Cynthia S. Pomerleau, Principal Investigator)

Service, Boards and Committees

Society for Research on Nicotine and Tobacco, Founding President; Chair of the Publications and Communications Council (1997-2000); Member of the Board of Trustees; Chair of the Pulications Committee and founder of the scientific journal, Nicotine and Tobacco Research; Chair of the Liaison Committee for the World Congress on Tobacco Or Health (2000).

University of Michigan Substance Abuse Research Center, member, Executive Committee, 1988-2000.

College for Problems on Drug Dependence, Working Group on Smoking, Tobacco, and Health Policy.

Editorial Boards: Addictive Behaviors, Journal of Substance Abuse, The International Journal of Smoking Cessation, Nicotine & Tobacco Research (Chair, Publications Committee).

Reviewer: Drug and Alcohol Dependence, Journal of Substance Abuse, Nicotine and Tobacco Research.
American Psychological Association, Public Policy Office, consultant to US Congress for Tobacco Settlement Legislation, 1997.

Advisory Board, Georgetown University Transdisciplinary Tobacco Use Research Center, 1999

Advisory Board, Brown University Transdisciplinary Tobacco Use Research Center, 1999

Advisor, National Cancer Institute Human Genetics Intramural Laboratory (Dean Hamer, Ph.D., Director), 1999

Nicotine Research Lab



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